Tuesday, February 7, 2023

Menopause / Hot Flashes

 

EPA Omega 3

Effects of ethyl-eicosapentaenoic acid omega-3 fatty acid supplementation on hot flashes and quality of life among middle-aged women

https://journals.lww.com/menopausejournal/Abstract/2009/16020/Effects_of_ethyl_eicosapentaenoic_acid_omega_3.22.aspx

Supplementation with E-EPA omega-3 fatty acid reduced HF frequency and improved the HF score relative to placebo. These results need to be confirmed by a clinical trial specifically designed to evaluate HFs in more symptomatic women.”

Black Cohosh – side effects aren’t good

Pilot Evaluation of Black Cohosh for the Treatment of Hot Flashes in Women

The reduction in mean daily hot flash frequency was 50% (95% CI, 34%–65%), while weekly hot flash scores were reduced 56% (95% CI, 40%–71%) at completion of the study. Overall, patients reported less trouble with sleeping, less fatigue, and less abnormal sweating. No patients stopped therapy because of adverse effects. Conclusions. Black cohosh appeared to reduce hot flashes and had a low toxicity. The efficacy found in this trial seems to be more than would be expected by a placebo effect (20%–30% hot flash reduction in previous trials).

Evening Primrose Oil

The effect of oral evening primrose oil on menopausal hot flashes: a randomized clinical trial

https://link.springer.com/article/10.1007/s00404-013-2852-6

The application of oral evening primrose oil compared with placebo for controlling hot flashes may decrease more the intensity of attacks as well as ameliorating the HFRDIS score.”

Licorice Root

Effects of Licorice on Relief and Recurrence of Menopausal Hot Flashes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832176/

“Findings showed that licorice root is effective in reducing the frequency and severity of hot flash. Comparing the mean frequencies of hot flash in the weeks before the therapy, 8 weeks of therapy and 4 weeks of follow-up through ANOVA with repeated measurements, there was found a significant difference in the licorice group and no difference in the placebo group. In other words, licorice could decrease daily hot flash frequencies during 8 weeks while no decrease was found at the same period in the other group. In addition, the significant difference in the licorice group was seen from the 1st week, increased significantly in time and continued until the 2nd week after the therapy as the recurrence took place from this stage.”

Anise – Pimpinella Anisum

The Study on the Effects of Pimpinella anisum on Relief and Recurrence of Menopausal Hot Flashes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813162/

In general, the results showed that Pimpinella anisum had desirable effects on severity and frequency of hot flashes.”

Sage Extract

The effect of Saliva officinalis extract on the menopausal symptoms in postmenopausal women: An RCT

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686654/

“It was concluded that Saliva officinalis were effective to change the severity of some of the menopausal symptoms in postmenopausal women.”

Fenugreek Seed 

Probable effects of fenugreek seed on hot flash in menopausal women

https://pesquisa.bvsalud.org/portal/resource/pt/emr-78018

“Use of fenugreek seed for four and eight weeks caused to decrease number of hot flashes and vasomotors, but the effect was smaller than that of HRT.”

Vitamin E

The Effect of Vitamin E on Hot Flashes in Menopausal Women

https://www.karger.com/Article/Abstract/106491

Based on our trial, vitamin E is recommended for the treatment of hot flashes.

Circumin + Vitamin E

The effect of oral capsule of curcumin and vitamin E on the hot flashes and anxiety in postmenopausal women: A triple blind randomised controlled trial

https://www.sciencedirect.com/science/article/abs/pii/S0965229919313068

The results of this study showed that oral intake of curcumin and vitamin E significantly reduced hot flashes in postmenopausal women but had no significant effect on anxiety, sexual function and menopausal symptoms.”

 

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